Chemist I - Oligonucleotide - Purification

Overview:

Business Title: Chemist I – Oligonucleotide Purification

Position Title: Analyst I

Division: Consumer Products Services

Entity: Consumer Products Services/ATL

Location: Boston, MA

Reports to: Manager

FLSA: Non-exempt

Hours Worked: Typically, Monday through Friday, forty-hours per week.

However, must be flexible to meet the needs of the department and complete other projects as assigned.

Position Summary:

The Chemist I is responsible for assisting with downstream processing of oligo synthesis using chromatography and analytical techniques. FPLC(Fast Protein Liquid Chromatography), HPLC, LCMS and other analytical instruments are used. This person will work on multiple projects simultaneously and stay current with new modifications of oligonucleotides.

Duties and Responsibilities:

It is everyone’s responsibility to live out our Values and Absolutes by Shaping a World of Trust while ensuring responsible progress.

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Purification: Perform purification of oligonucleotides as needed using techniques such as FPLC and HPLC and monitoring purification processes to achieve high quality results.

Analysis: Conduct analytical assays including LCMS to verify the quality and identity of synthesized oligonucleotides

Maintenance: Support scientists in building and executing clean-in-place procedures, along with instrument hardware upgrades to improve workflows.

Documentation: Maintain accurate and detailed records of experiments, procedures, and results using ELNS. Ensure all documentation is compliant with company standards and regulatory requirements.

Lab Maintenance: Contribute to the maintenance of the laboratory.

Collaboration: Work closely with senior chemists and other team members to support ongoing projects.

Use of general laboratory equipment including but not limited to pipettors, centrifuges, incubators, biological safety cabinets and balances

Software includes instrument-specific for capturing and analyzing data, Microsoft Office (Word, Excel, PowerPoint, Outlook, Teams/Sharepoint, etc), LIMS, electronic laboratory notebooks, etc.

Identify, troubleshoot, and suggest technical solutions to clients and management

Follow the guidelines set forth with clients and Company Quality, Health, Safety, Security and Environmental policies and procedures.

Comply with clients’ and Company management systems in accordance with appropriate regulatory agencies.

Other duties as defined by the Manager, department needs and workload

Skills & Proficiencies:

Strong laboratory skills and experience with analytical instrumentation such as AKTA, Agilent LC-MS and UPLC, Vanquish LTQ, Water’s QDA, as well as basic laboratory techniques and equipment (pipetting, mass spectrometry, chromatography) is required

Basic understanding of chemistry and chromatography

Strong organizational skills and time management skills

Effective communication skills for collaborating with team members and conveying technical information clearly.

Strong problem-solving abilities and critical thinking skills

Ability to organize and prioritize workload to meet or exceed deadlines

Individual and Team work ethic

Proficiency with Windows, Word & Excel

Strong attention to detail and ability to follow protocols precisely

Positive attitude, self-motivated, high level of engagement

Eagerness to learn and adapt in a fast paced environment

Champions and adheres to company values including team engagement

Education and Experience:

Degree requirement: Bachelor's Degree in Chemistry, Chemical/Biomedical engineering, pharmaceutical sciences or a related field with 1 year of lab experience that may include coop or internships

Compensation Range: $33.00-$37.00 per hour (e.g., the job posting is not necessarily reflective of actual compensation that may be earned, and actual compensation is subject to variation due to such factors as location, education, experience, and skillset).